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In observance of a holiday, Agilent CrossLab/iLab Operations Software Support Help Desk will be closed during U.S. hours on Monday, September 1st, 2025. We will resume regular U.S. support hours on Tuesday, September 2nd, 2025. EU and APAC Support will remain open during this time. For urgent matters, please add "Urgent" to the ticket/email subject or press "1" when prompted to escalate a call on the iLab Support phone, and we will prioritize those requests first.

Cryo-Electron Microscopy Facility (Huck)

RRID:SCR_024456

Overview of Services

This Facility is built around the capabilities of our Thermo Fisher Titan Krios and Talos Arctica microscopes. Installed between Spring 2017 and Fall 2019, this revolutionary, cryo-based technology permits a full range of semi-automated applications, including 2D electron crystallography, single particle analysis, cryo-electron microscopy, and cellular tomography of frozen hydrated cell organelles and cells.

In 2025, the Hyra FIB-SEM is installed. This equipment has 4 ion beams that can provide faster lamella milling under cryo conditions. The addition of the IFLM fluorescence microscope enables the accurate targeting the cellular structures for lamella milling and slice viewing.

Leadership

Steering Committee

  • Wen Jiang, Faculty Director | Professor of Biochemistry and Molecular Biology
  • Katsu Murakami, | Professor of Biochemistry and Molecular Biology
  • Song Tan | Professor of Biochemistry and Molecular Biology
  • Clive Randall | Professor of Materials Science & Engineering, Director of the Materials Research Institute
  • Enrique Gomez | Professor of Chemical Engineering
  • Jean Paul Armache | Assistant Professor of Biochemistry and Molecular Biology

Location and hours of operation

Hours Location
Monday - Friday
9:00 am - 5:00 pm

24/7 card swipe access for trained users       

N-030-H, N-032 & N-034-A Millennium Science Complex
University Park, PA 16802

 

Links and Resources

 

Contacts

Name Role Phone Email Location
Sung Hyun (Joseph) Cho
Co-director, CryoEM Facility
 
814-865-5729
 
sxc73@psu.edu
 
W249 Millennium Science Complex
 
Jenny Wang
Co-director, Cryo-EM Facility
 
8148651158
 
zw691551@psu.edu
 
W252 Millennium Science Complex
 

Service list


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Consumables (7)
Microscopy Services (4)