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Advanced Light Microscopy (COM)

Overview of Services

Advanced Light Microscopy Imaging Core at the Penn State Hershey provides training and consultation in ultra-high resolution imaging of cells and tissues in fixed or live states using high end multimodal light microscope systems. We also provide expert advice in quantitative image analysis and offer collaborative opportunities, including image processing, image analysis and data interpretation in microscopy related research projects. Our Confocal, Super-resolution STED and Deconvolution  Microscopes are useful in 3D imaging of any biological systems and spatial distribution of multiple fluorescently labelled sub-cellular objects including various cellular proteins complexes (multiple colors) simultaneously in live or fixed biological conditions. We are also equipped with a Multimodal Multiphoton Microscope which is capable of performing deep tissue fluorescence (multiple colors) and harmonic generation imaging in ex vivo, in vivo or intra-vital small animal imaging. Our IMARIS, VOLOCITY and HUYGENS Workstations are excellent tools for 3D reconstruction from a series of 2D optical sections as well as complex quantitative microscopy computations. 
  • For training on any of the advanced light microscopy methods and for consultation relevant to advanced light microscopy imaging projects, please send an email to

  Dr. Thomas Abraham, Director of Advanced Light Microscopy Imaging

  at or


Bruce Stanley | Director, Scientific Programs

Thomas Abraham, PhD | Director/ Associate Professor

Wade Edris, MS | Research Tech

Location and hours of operation

Hours Location

Monday - Friday

8:00 am - 5:00 pm

24/7 Access to Trained Users           


Room C1730, 1728, C1732A

500 University Dr.

Hershey, PA 17033

Links and Resources


Name Role Phone Email Location
Thomas Abraham, PhD
Director/ Associate Professor
(717) 531-0003 x285486
Bruce Stanley
Director, Scientific Programs
(717) 531-5329