Transmission Electron Microscopy (COM)


Overview of Services

Our mission is to provide high-quality transmission electron microscopy (TEM) services, education, and training for the Penn State Hershey campus, other academic institutions, and private companies at-large.

The lab is equipped with high-resolution transmission electron microscopes (JEOL 1400) and a full suite of ancillary sample preparation equipment to fit most TEM-related needs. The equipment can provide nanometer-scale analysis for biological, chemical, and materials science. The TEM facility offers multiple levels of service that correspond with the services and training each user desires:

  • Project consultation
  • Education and training for new users
  • Full-service transmission electron microscopy.

TEM services include sample preparation, fixation, embedding, ultra-microtomy, staining, TEM imaging, immuno-localization (i.e. immunogold EM), and negative staining.

TEM Applications

TEM can be used to obtain a detailed view of a specimen at the atomic resolution level. For biological samples, TEM can give unambiguous identification of cellular compartments and organelles. In combination with a specific molecular marker (e.g. antibody) and electron-dense labels (immunogold particles or Nanoparticles), it is possible to identify the association of particular molecules with a specific organelle or with another type of molecule.




Han Chen | Manager

Location and hours of operation

Hours Location

Monday - Friday

8am - 5pm                   


Room C1727

500 University Dr.

Hershey, PA 17033


Links and Resources


Name Role Phone Email Location
Han Chen