Cryo-Electron Microscopy (COM)

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Cryo-Electron Microscopy - Penn State College of Medicine Research (

Please contact us by email if you would like to learn more about how CryoET or CryoEM can further your research. We will be happy to schedule a time to discuss in person, by phone, or via Zoom.


Name Role Phone Email Location

Overview of Services

The PSU College of Medicine (COM) cryoEM core  provides access to state-of-the-art cryoEM and cryoFluorescence instruments.

Services Offered

Single Particle Data Collection

Tomographic Data collection

Cryo Correlative Light and Electron Microscopy

Cryo or room temperature imaging of stained or unstained samples

Sample preparation including vitrification and clipping

Training on sample preparation, microscope operation, screening, and data collection


Titan Krios (equipped with Volta Phase Plates, Bioquantum Energy Filter and K3 Direct Electron Detector), Suite 149 NMR Building

Jeol 2100 (Cryo side-entry Holder), Room C1724A

Zeiss LSM 980 Cryo-Confocal, Room C1733

Vitrobot Mark IV, Room C1724


Matt Swulius, CryoET Director
Ken Lee, CryoEM Director, SPA

 Location and hours of operation

Call or text Lab Manager Jen at 814-441-2723, 9am -9pm

Hours Location

8 am - 5 pm Monday - Friday 

 NMR Research Building, Rm 149

Links and Resources

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Name Role Phone Email Location
Matt Swulius
Faculty Co-Director (Tomography)

Ken Lee
Faculty Co-Director (Single Particle)

Jen Sloppy
Core Manager


Service list

Search available services: View: by category alphabetically
Consumables (1)
Microscopy Services (2)