The Advanced Light Microscopy Core at Penn State College of Medicine offers consultation and training for fluorescence imaging of molecules, cells, tissues, organs, and embryos. Additionally, we provide access to commercial software for image visualization/processing/analysis and can offer expert advice in quantitative image analysis.

Provides a non-invasive way to track and quantify bioluminescent and fluorescent signals in cells or in whole animals.

Facilitate cutting-edge research by providing this state-of-the-art fluorescence-activated cell sorting and analytical services at reasonable hourly rates.

Provides consultation, instrumentation, and services in genomic, epigenomic and transcriptomic studies. Has capabilities ranging from highly focused analysis of candidate SNPs and mRNAs to whole genome, exome, epigenome and transcriptome sequencing.

Our mission is to provide high-quality transmission electron microscopy (TEM) services, education, and training for the Penn State Hershey campus, other academic institutions, and private companies at-large.

The Advanced Manufacturing and Innovation Center (AMIC) building, located in Knowledge Park near Penn State Behrend's campus, houses multiple load frames, an AFM, an ESEM, hardness testers, optical microscopes, sample preparation equipment, and an optical profilometry instrument. 

The Jack Burke Research and Economic Development Center building, located on Penn State Behrend's campus, contains both manufacturing equipment and characterization instrumentation for polymers, metallic materials, and electronic materials. 

The Otto Behrend Sciences building and Yahn Planetarium are part of the School of Science at Penn State Behrend. Characterization equipment includes multiple mass spectrometers (GC-MS, LC-MS, ICP-MS), light spectrometers (FTIRs), a nuclear magnetic resonance (NMR) instrument, and calorimeters.

The Plastics Processing Lab, located in 127 Burke, is a multi-million dollar state-of-the-art processing lab. All major plastic conversion processes are represented in the 10,300-square-foot facility. 

The maintenance shop provides an array of repair and renovation services. The pump shop provides pump repair, pump maintenance, pump overhaul, and all your vacuum pump needs.

A full service facility capable of fabricating scientific glassware, both simple and complex.

This service allows researchers to have their liquid nitrogen dewars filled.

The Penn State Nuclear Magnetic Resonance Spectroscopy (NMR) is a state-of-the-art campus wide Facility that houses ten high-resolution Bruker NMR instruments (300 MHz to 850 MHz) with a wide range of capabilities: high-sensitivity cryoprobes, high-throughput sample changers, solid state probe...

Provides cost-effective and high quality services for design and fabrication of custom instrumentation and the maintenance and repair of equipment which is used throughout the Penn State community.

Crystal growth, single crystal structure determination and data analysis of small molecule samples can be performed at the facility.

A wet lab specially designed for ELISA, Multiplex assays, and Telomere length analysis. This shared use facility is setup for complete sample analysis, sample organization, sample aliquoting, long-term sample storage and independent use of lab equipment by PIs and their research staff.

The CTSI fosters an environment that allows research discoveries to quickly and efficiently develop into health benefits.

Providing high-throughput thermodynamic analysis of biological macromolecule binding and folding to University and outside researchers.

Facilitating bioprocessing services by providing equipment and expertise to university-affiliated and independent governmental and industrial researchers.

Providing services in all aspects of optical and electron microscopy, histology, flow cytometry, and cell sorting.

Providing services in all aspects of flow cytometry, and cell sorting.

Providing next-generation sequencing and a number of traditional genomic services to the Penn State community as well as those outside the University.

Providing in vivo imaging and magnetic resonance microscopy services via custom-designed experiments.

The Facility is specialized in three clusters – optical microscopy, electron microscopy and histology – equipped with confocal microscopes, research fluorescence microscopes, transmission- and scanning electron microscopes.

Offering nominal and accurate MS analysis, and providing identification and quantitation of metabolites by LC-MS or LC-MS-MS, and protein sample identification by LC-ESI-MS-MS, or MALDI-TOF-TOF-MS.

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Providing training, assistance and expertise in crystallizing and determining the three-dimensional structures of proteins and other biological macromolecules.

Conducting mass spectrometry-based metabolomics studies on a variety of biofluids and tissue extracts from plant and animal sources.

Provides high-performance computing solutions through the Advanced CyberInfrastructure (ICDS-ACI) system.

The SLEIC is dedicated to fostering cutting edge research in the social, behavioral, biological, engineering, and materials sciences where imaging methodologies play a central role.